AOD-9604
Fragment of hGH (176-191) studied in lipid metabolism research.
Evidence Level
Low
Research Type
/ System Mapping
Where this compound appears in research pathways
Research-only note: This mapping is educational and does not represent a treatment protocol.
/ 01
Overview
Fragment of hGH (176-191) studied in lipid metabolism research.
/ 02
Mechanism of Action
Studied for lipolytic signaling without GH-like growth effects.
/ 03
Research Applications
Fat oxidation pathway research.
Studied for, research explores, preclinical models suggest, clinical studies have investigated.
/ 04
Studied Research Contexts
/ 05
Studied Research Dosing Ranges
Limited public data on dosing ranges across research models.
/ 06
Potential Adverse Effects Reported in Research
Adverse effect data is limited. Many compounds in this database lack human safety profiles.
/ 07
Mechanism Deep Dive
AOD-9604 is a fragment derived from the C-terminus of human growth hormone. Preclinical research describes interactions with lipolytic signaling and beta-adrenergic pathways, with reported effects on fat oxidation in animal models.
/ 08
Pathway Role
Sits within lipid metabolism and adrenergic signaling pathways at the adipocyte level in preclinical models.
/ 09
Biological Targets
/ 10
Research Applications
- Preclinical obesity and lipid metabolism studies
- Adipose tissue signaling research
/ 11
Evidence Summary
Animal data provides the strongest mechanistic signal. Human outcome data is weak or mixed.
Evidence Level Rationale
Rated low because human clinical outcome trials have not consistently supported the preclinical lipolytic signal.
/ 12
Research Observation Timeline
Early Signal Window
Acute lipolytic markers in animal models within days
Primary Study Window
Preclinical studies often used short windows (e.g. 14 days in obese mice)
Endpoint Type
Biomarker and adipose tissue endpoints
Evidence Strength
Low / mixed for human outcomes
/ 13
Safety & Unknowns
Limited human safety data. Long-term human outcome and safety profile is not characterized.
/ 14
Research Limitations
Reliance on short rodent studies. Translation to human body composition outcomes is not established.
/ 15
References
References are being curated from peer-reviewed literature.
/ 07
Evidence Score
Overall Research Confidence
Low
Reflects breadth of mechanism, study type, and reproducibility across research literature.
/ 08
Related Peptides
Tesamorelin
GHRH analog studied for visceral adiposity research.
SS-31
Elamipretide
Mitochondrially-targeted tetrapeptide studied for cardiolipin interaction.
MOTS-c
Mitochondrial-derived peptide studied in AMPK signaling research.
Appears in pathways
For research and educational purposes only.
Not medical advice. Not intended to diagnose, treat, cure, or prevent disease. Compounds discussed may not be approved for human use. Any dosing information shown describes ranges studied in research settings — never a recommendation.